SD Pharmaceuticals : Apigenin 99
Every capsule of SD Pharmaceuticalsâ APIGENIN 99 delivers 50 milligrams of pure apigenin, which is derived from the chamomile plant (Matricaria chamomilla). APIGENIN 99 was developed based on the body of research findings that have examined its anti-aromatase and estrogen-modulating properties.* More specifically, apigenin has been studied for its effects on aromatase mRNA gene expression.*
WHAT IS APIGENIN?
Apigenin is a natural flavonoid thatâs found in many fruits and vegetables, including parsley, celery and chamomile. In addition to its anti-aromatase properties, apigenin has also been studied for its antioxidant, anti-inflammatory, cardiovascular and antibacterial properties.*
What are flavonoids?
Flavonoids are a class of plant secondary metabolites. They fulfill many different functions in plants. They are most important for plant pigmentation for the coloring of flowers. They are also involved in UV filtration and act as chemical messengers and physiological regulators.*
There are 3 main classes of flavonoids:
- Flavonoids (Bioflavonoids)
Flavanoids are slightly different structures than flavonoids (they are non-ketone-containing structures, whereas flavonoids are ketone-containing).
Flavonoids are broken down into 5 subgroups:
- Anthoxanthins (Flavones and Flavonols)
Apigenin falls into the class of anthoxanthin (flavone).
HOW DOES APIGENIN WORK?
Research suggests that apigenin has anti-aromatase properties via two pathways:
- Research suggests that apigenin has anti-aromatase activity properties.* Aromatase is the enzyme responsible for converting testosterone to estrogen. Inhibition of the aromatase enzyme helps reduce the amount of testosterone that gets converted to estrogen. Healthy regulation of the aromatase enzyme can help support healthy testosterone and estrogen levels.*
- Research suggests that apigenin has anti-aromatase mRNA expression properties. The main function of RNA is to carry amino acid sequence information from the genes to where proteins are assembled on ribosomes in the cytoplasm. This is done by messenger RNA (mRNA), which is a large family of RNA molecules that convey genetic information from DNA to the ribosome, where they specify the amino acid sequence of the protein products of gene expression. Research suggests that apigenin can affect aromatase mRNA expression.*