Olympus Labs EP1LOGUE Review | Epicatechin Re-Invented

blog-icon By TJ Posted on October 13, 2017

The EP1LOGUE Promise

Olympus Labs is at it again, this time introducing a product that is centered on the elusive Epicatechin. This is not the company’s first venture with the ingredient, however. Their last reveal, the EP1C  didn’t really deliver on its promise because Epicatechin was found to have low bioavailability. 

The company’s Research and Development department appears to have been running on full throttle lately and this time, the company has promised to up its game with the incorporation of Epicatechin PhytoFUSE into its latest product, EP1LOGUE. EP1LOGUE promises to maximize results while keeping the formula simple. Intrigued? So are we. So, in this Olympus Labs EP1LOGUE review, we will evaluate the promises made by EP1LOGUE & see if we can give it the nod.

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Muscle Mass Growth with Epicatechin PhytoFUSE (600mg)

Put on your science lab robes, we are going to have to sound a bit scientific here. It is a common misconception that all kinds of proteins are beneficial for gaining muscle mass. The reality is entirely different because there are proteins—such as myostatin—that can prevent a fitness enthusiast from gaining muscle mass by inhibiting differentiation and muscle cell growth. In order to prevent your hard work from being wasted, it is important to inhibit myostatin so that you do not lose out on those priceless gains. This is where Epicatechin enters into the picture

Epicatechin is a flavanol found in green tea and cocoa seeds, Epicatechin can be used to inhibit myostatin because it converts to follistatin in our bodies. Follistatin, for those who do not know, is a protein that inhibits myostatin, by a factor of 2.5x. It binds onto this pesky muscle growth inhibiting protein and prevents it from ransacking your efforts. However, as Olympus Labs found with EP1C, Epicatechin has a poor bioavailability when it comes to humans, regardless of how successful it might have proved to be on rodents. Humans and rodents are just not alike, sadly (when it comes to the utilization of Epicatechin, at least!).

Learning from the failure of EP1C—Olympus Labs has decided to make use of Epicatechin PhytoFUSE in EP1LOGUE. PhytoFUSE is a patented and unique delivery technology that promises to enhance the bioavailability and delivery of Epicatechin, anywhere from two to six times. Does this sound too good to be true? According to the company, PhytoFUSE does this by the molecular utilization of specific complex and lipids, which enhance the solubility and absorption of Epicatechin in the human system. It transports the active ingredients straight to the intestines, where they can be delivered to the bloodstream and utilized for the purpose of protecting the muscles from the detrimental effects of myostatin. Human tests and demonstrations of PhytoFUSE indicate that it is safe to use and does not have any repercussions on the users’ health.


Ok, take off that robe for a second, said simply, Epicatechin can help with Myostatin inhibition which means more muscle. The problem is that Epicatechin has crappy bio-availability in humans. Olympus Labs EP1LOGUE uses a new delivery technology that has been shown to increase the bioavailability of Epicatechin in humans. Boom!


Increased Muscle Endurance and N.O. Boost with Vaso6 (300mg)

Vaso6 is becoming a popular choice for N.O supplementation. We saw Olympus Labs make use of it very successfully in RE1GN. Vaso6 is derived from the extracts of green tea or grape seed and is known to stimulate the production of nitric oxide. Vaso6 is also known as “super Epicatechin” because it contains only those fractions of grape seed extracts that offer the highest EDR activity (necessary for the release of nitric oxide). What this means is that the only ingredients of grape seeds’ extract included in Vaso6 are the ones that encourage the release of nitric oxide and increase blood flow and vasodilation.

Vaso6 is known for its effectiveness. It stimulates nitric oxide at exaggerated levels that are 10x higher than what citrulline can offer.

Vaso6 is most effective when consumed before workouts. The enhanced blood flow transports important nutrients to metabolic targets which, in turn, activates Muscle Protein Synthesis (MPS). MPS is also triggered by Vaso6 because the generation of peroxynitrite activates TRPV1, which increases intracellular Ca2+ levels, resulting in the activation of TORC1. TORC1, as most fitness enthusiasts know, benefits MPS. The NO released by Vaso6 also triggers muscle hypertrophy. This is why the use of Vaso6 leads to stronger pumps during workouts.


Vaso6 gives Epicatechin PhytoFUSE a kind of turbo-boost with its enhancement of endurance and workout appetite. The fact that it also increases blood flow means MPS is activated, granting better performance and bigger pumps to the fitness enthusiasts that rely on its magic.


Build Skeletal Muscle Mass with Urolithin B (150mg)

According to research, ellagitannins prevents your muscles from being damaged as a result of intense workouts and, at the same time, protects them from any amount of stress that might be induced by such diets that are full of fats. The surprising thing is that ellagitannins have a low bioavailability, meaning that it is the metabolites that are derived from ellagitannin that is responsible for the wonderful effects. Urolithin D is the first metabolite to be produced in the human body, while Urolithins A, B, and C are formed as Urolithin D loses hydroxyl groups. It is Urolithin B, though, that has encapsulated the attention of researchers and fitness enthusiasts alike!

When clinical research was carried out on urolithins, it was found that the myotubes in culture were bigger after Urolithin B was incubated.When it was tested in the labs, the metabolite was also found to reduce muscle atrophy and enhance muscle hypertrophy, indicating that it helped build lean mass and prevented muscle breakdown


What this means is that Urolithin B, if used correctly, holds interesting potential for the growth of skeletal muscle mass. 


The Label’s Bottom Line 

EP1LOGUE’s formula is pretty simple (also compared to the alternative) with only three core ingredients. However, when you look at the choice of these 3 and the interesting research behind them, we have to say that the three ingredients appear to have most of the bases covered and brings in a unique combo to the muscle growth game. You obviously know by now that nothing works unless you do, and you should know that EP1LOGUE is not designed to give you instant results—owing to the natures of the ingredients used—and will need to be consumed regularly and for an extended period of time to yield and maintain the promised results.

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